Methylation factor MRPL15 identified as a potential biological target in Alzheimer’s disease
نویسندگان
چکیده
منابع مشابه
AGE proteins as a causative factor in Alzheimer's Disease
The reaction between reducing sugars and protein free amines, known as the Maillar reaction results in the formation of advanced glycation endproducts (AGEs). AGE modification changes the structure of proteins to amyloid cross-beta structure. These protein structures can activate receptors known as RAGE on glial cells (microglia and astrocytes), and induce the expression of inducible nitric oxi...
متن کاملAGE proteins as a causative factor in Alzheimer's Disease
The reaction between reducing sugars and protein free amines, known as the Maillar reaction results in the formation of advanced glycation endproducts (AGEs). AGE modification changes the structure of proteins to amyloid cross-beta structure. These protein structures can activate receptors known as RAGE on glial cells (microglia and astrocytes), and induce the expression of inducible nitric oxi...
متن کاملMaternal Periodontal Disease as a Potential Risk Factor for Preterm Birth and Low Birth Weight
Background and Aim: Periodontal disease may cause adverse pregnancy outcomes such as low birth weight (LBW) or preterm birth (PTB). In the present study, mothers with one of these two delivery complications were analyzed regarding presence/absence of periodontal disease as a possible risk factor in comparison with related medical risk factors. Materials and Methods: In this cross-sectiona...
متن کاملApoptosis as a Potential Target in Therapeutic and Vaccine Interventions against Parasitic Diseases
Apoptosis is a physiological cell death that occurs under normal conditions in major biological processes, including the removal of old, damaged, extra, or harmful cells. It plays an important role in natural evolution, tissue homeostasis, removal of cells damaged or infected by viruses, and removal of immune cells activated against self-antigens. The purpose of this review was to examine the r...
متن کاملCARD9 as a potential target in cardiovascular disease
Systemic inflammation and localized macrophage infiltration have been implicated in cardiovascular pathologies, including coronary artery disease, carotid atherosclerosis, heart failure, obesity-associated heart dysfunction, and cardiac fibrosis. Inflammation induces macrophage infiltration and activation and release of cytokines and chemokines, causing tissue dysfunction by instigating a posit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Aging
سال: 2021
ISSN: 1945-4589
DOI: 10.18632/aging.202862